Taizhou Zecen Biotech Co.,Ltd.
Innovation For Health,Quality For Life
Add to Cart
Kidney Function Kit for Chemiluminescence Immunoassay Analyzer NGAL H-ALB RBP Cys-C β2-MG
| Kidney Function | NGAL | NGAL is a growth factor in physiological state, mainly involved in the occurrence and growth of early renal epithelium. The expression level is lower in normal tissues including kidney, lung, stomach and colon epithelial tissues. In the process of ischemic and toxic kidney injury, NGAL in renal tubular epithelial cells will increase significantly, and within the first two hours, NGAL levels in urine and blood will increase significantly, so NGAL is an early stage of acute kidney injury. sensitive markers. NGAL is also a potential new marker to reflect chronic kidney damage. In patients with chronic kidney disease (CKD), NGAL can accurately reflect the degree of kidney damage and is a strong and independent risk indicator for CKD progression. . |
| H-ALB | Normally, a urine test should be negative for albumin. When renal function is impaired, the permeability of the glomerular basement membrane increases, resulting in an increase in urinary protein or microalbumin. Urinary microalbumin (H-ALB) indicates abnormal renal leakage of protein, which not only reflects the impairment of glomerular filtration function, but also reflects the impairment of renal tubular reabsorption function. The increase of microalbumin excretion represents the early changes of the disease, and has important reference value and clinical significance for the early diagnosis and early treatment of the disease. Microalbumin is a marker of early renal damage and an independent predictor of the degree of progressive damage in hypertensive nephropathy and diabetic nephropathy. | |
| RBP | Retinol-binding protein is a protein involved in the transport of vitamin A in the blood, synthesized by the liver and widely distributed in blood, cerebrospinal fluid, urine and other body fluids. Determination of retinol-binding protein can early detection of renal tubular damage, and can sensitively reflect the degree of damage to proximal renal tubules, and can also be used as an indicator of early damage to liver function and monitoring and treatment. Reduce: vitamin A deficiency, hypoproteinemia, malabsorption syndrome, liver disease (except for fatty liver with excess nutrition), obstructive jaundice, hyperthyroidism, infectious disease, trauma, etc. Elevated: renal insufficiency, overnutrition fatty liver. | |
| Cys-C | Cancer treatment impairs kidney function, so oncology uses cystatin C as a marker for diagnosing early impairment of kidney function in order to adjust drug dosage and prevent irreversible kidney damage. Reducing protein intake or muscle wasting in cancer patients can prevent the rise in creatinine levels in kidney failure. Therefore, cystatin C provides important information for the detection of renal function. | |
| β2-MG | The clinical detection of β2-MG concentration in blood or urine provides an early, reliable and sensitive indicator for clinical diagnosis of renal function determination, renal transplantation survival, diabetic nephropathy, heavy metal cadmium, mercury poisoning and some malignant tumors. The detection of β2-MG in cerebrospinal fluid has special significance for the diagnosis of meningeal leukemia. |
